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chloramphenicol_Khyati Jain

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Study on Chloramphenicol resistance pattern in Central India, Indore

Jain K,1 Tripathi S2

Assistant Professor,1 Professor2

1Department of Microbiology,Index Medical College Hospital & Research Centre, Indore, Madhya Pradesh, India

2Department of Pharmacology, Index Medical College Hospital & Research Centre, Indore, Madhya Pradesh, India

ABSTRACT
BackgroundChloramphenicol (CK) is drug of choice in many life threatening and serious bacterial infections. Due to development of resistance and toxicity associated with this drug, it is not in common use now days. This study was done to find out prevalence of CK resistance pattern.Material Methods100 consecutive pus samples from surgical site infections from various specialties of index medical college hospital and research center were studied in microbiology department during period of 1year. Results

Gram positive as well as Gram negative organisms had shown sensitivity to Chloramphenicol. Also organisms were resistant to commonly used higher antibiotics.

Conclusion

CK can be used for common serious IPD patients not having contraindication to this drug. Study also reinforces proper and rational use of antibiotics.

KEY WORDS
Chloramphenicol, drug resistance, gram positive and gram negative organism.

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CUSHING’S SYNDROME AND ADRENAL SUPPRESSION FOLLOWING TOPICAL CORTICOSTEROID USE

Shamsudden A,1 Remorino R,2

Paediatric Registrar,1 Consultant Paediatrician2

1Department of Pediatrics, Leeds general Infirmary, United Kingdom

2Department of Pediatrics, St Richards Hospital, Chichester ,United Kingdom

ABSTRACT
The extended use of topical corticosteroids, particularly in young children, may cause suppression of the hypothalamo-pituitary-adrenal axis. Here, three cases of iatrogenic adrenal suppression resulting from topical corticosteroids are presented.
KEY WORDS
Adrenal insufficiency, Corticosteroid, Iatrogenic cushing’s syndrome.

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